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Advantage II for Dogs

By Advantage
(91 reviews)
Veterinary Diet Item
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Advantage II for Dogs

By Advantage
$50.99
One-time purchase
$30.99 AutoShip & Save up to 40%
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Product Overview

Advantage II for Dogs is a topical flea control formula that kills adult fleas and inhibits the flea life cycle at all stages. Adult fleas are killed within 12 hours, giving your pet fast relief. Advantage II continues to work for a full month and provides effective protection from lice—all with an easy-to-apply topical.

Note* See Allivet’s Flea and Tick Chart to refer to which flea and tick treatment your pet may require.


Advantage II provides effective flea and lice protection in a monthly topical that is easy to use. It’s for dogs and puppies older than 7 weeks old.
Advantage II is indicated for use in dogs or puppies older than 7 weeks of age. Consult with your veterinarian for more details.
Advantage II for dogs is an easy-to-use monthly topical that kills adult fleas and stops the flea and lice lifecycles. The product is safe, waterproof, and fragrance-free.
The active ingredients in Advantage II, Imidacloprid and Pyriproxyfen, kill adult fleas and stop the flea lifecycle in its tracks.
  • Imidacloprid…………….9.10%
  • Pyriproxyfen……………0.46%
  • Other Ingredients………90.44%
  • Total…………………….100.00%
Contact your closest emergency pet hospital.
Not safe for puppies 7 weeks of age and younger.
Small Dogs (Up to 10 lbs) Green (in 4 month, 6 month or 12 month supplies) Medium Dogs (11-20 lbs) Teal (in 4 month, 6 month or 12 month supplies) Large Dogs (21-55 lbs) Red (in 4 month, 6 month or 12 month supplies) Extra Large Dogs (Over 55 lbs) Blue (in 4 month, 6 month or 12 month supplies)
Elanco
HOW TO APPLY
1. Remove one applicator tube from the package. See “HOW TO OPEN” section.
2. Hold applicator tube in an upright position facing away from you and your pet‘s face and eyes. Pull cap off tube.
3. Turn the cap around and place other end of cap back on tube.
4. Twist cap to break seal, then remove cap from tube.
5. The dog should be standing for easy application. Part the hair on the dog’s back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your dog’s eyes or allow your dog to ingest this product. Do not allow the product to run off.
6. The dogs should be standing for easy application. apply the entire contents of the tube evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog‘s eyes or allow your dog to ingest this product.
7. Discard empty tube as described in the Storage and Disposal section.
8. Under normal conditions the product is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven (7) days. After flea control is attained, return to a monthly retreatment schedule.
Imidacloprid…………….9.10%
Pyriproxyfen……………0.46%
Other Ingredients………90.44%
Total…………………….100.00%

About This Product

Customer Reviews

4.8
91 reviews
5 78
4 12
3 1
2 0
1 0
Doris S Verified Purchase
April 16, 2026

I remember when the first Advantage hit the market in the late 90s, it was a huge game changer and I've used the product on my various dogs over the years and never had a problem.

Maria T Verified Purchase
January 2, 2024

This product I bought for my dashaund is for fleas an ticks an I use it on him every month this way I know he is protected. I have been giving it to him since he was a puppy he is now two an I love him just as one of my children

Ronald R Verified Purchase
April 16, 2023

This product works magnificently and they will eliminate the pests menacing our furry loved ones.

Kathleen S Verified Purchase
February 15, 2023

I have used Advantage II for many years on many different fur babies. It 100% works and so I don't change.

Kit p Verified Purchase
December 14, 2022

I have used this product for 12 years with no side effects.

Mary S Verified Purchase
November 3, 2022

If you are not able to get the oral medication advantage 2 works the best for topical .

April G Verified Purchase
January 26, 2022

Never had a problem with Advantage. I feel secure as a multiple dog owner.

Rebecca M Verified Purchase
August 30, 2021

It works well for my cattery.

Cynthia A Verified Purchase
August 18, 2021

Heart worm and fleas, that’s Florida! I looked for a product that would deal with all stages of fleas on my older dog, and the Allivet chart helped me make this choice. Thank you.

Cynthia B Verified Purchase
July 23, 2021

Great price, and auto-ship service.

Penny D Verified Purchase
May 3, 2021

Fast and easy. Thank you. I like easy online buying

KImberly R Verified Purchase
April 26, 2021

Good PRice and refills auto matic with a discount!!!

Penny D Verified Purchase
December 11, 2020

I bought for all the dogs and my cat cuz they have fleas. I want to thank you for fast and easy ordering and shipping. So far so good. Thank you

Karen E Verified Purchase
July 22, 2020

I have used this on all my dogs and this one works the best, never gets any ticks or anything

Ruthie S Verified Purchase
July 17, 2020

This has worked to keep fleas off my dog before and it’s supposed to be non-toxic

Cynthia M Verified Purchase
April 7, 2020

It works great

Susan H Verified Purchase
April 7, 2020

No fleas! Same ingredient as cat (just larger amount) so safer to use with cats in household

Denise D Verified Purchase
April 7, 2020

I don't love the smell of this on my pets for the first 24 hours but it does work to keep the fleas off. We live in the country with a lot of wild deer and turkey coming through so without this, our pets would suffer from constant bombardment. Highly recommended

Dahena V Verified Purchase
January 20, 2020

great price

Paige G Verified Purchase
December 10, 2019

This size is the most economical way to make multiple smaller doses for our many cats. We use small oral syringes for the cat doses to measure out the proper amounts based on the cats' weights. We save significantly more this way than buying the cat packages.

Maggie H Verified Purchase
December 4, 2019

Been using this for years, it never disappoints,

Ashlee P Verified Purchase
September 17, 2019

Great stuff

Georgia B Verified Purchase
September 17, 2019

I have used advantage to for years on my dogs. I am here to tell you I have never had a flea or tick problem. If something works you continue using it.

Anthony B Verified Purchase
August 26, 2019

Always an easy purchase and excellent price

Bj a Verified Purchase
August 9, 2019

No fleas ever

Debbie C Verified Purchase
July 22, 2019

Allivet contacts my vet for me!

Penny W Verified Purchase
July 12, 2019

Nothing works as good as the Advantage II on my dogs.

Peter S Verified Purchase
June 24, 2019

Low price!

Ola M Verified Purchase
June 18, 2019

This is the best for dogs that I have ever used and such a good price.

Michelle J Verified Purchase
June 12, 2019

Works fast. Highly recommend. Within 24 hours my dog had no fleas, no digging and scratching.

Melissa W Verified Purchase
June 6, 2019

Advantage has been the only good medicine that works good for dogs that live in the woods

Maggie H Verified Purchase
May 29, 2019

Best price .

Kyle C Verified Purchase
May 23, 2019

Trusted

Dora G Verified Purchase
April 22, 2019

The Prices are very good.

Kirsten S Verified Purchase
March 28, 2019

We have many mosquitos

Cheryl T Verified Purchase
March 18, 2019

Great price

Cheryl T Verified Purchase
March 18, 2019

Great price

Catherine C Verified Purchase
March 11, 2019

Great price! Easy ordering from home!

Maggie H Verified Purchase
November 1, 2018

Works for me.

Scott J Verified Purchase
August 22, 2018

Good job

Darla D Verified Purchase
July 31, 2018

I buy Advantage 2 55lbs + and dose it out because I have multiple dogs. I learned this trick working at the local Rescue. That's how they buy it and can treat multiple dogs and different sizes. All of mine are the same size and breed so it's easy.

Rhena H Verified Purchase
May 8, 2018

great flea/tic protection

Ronnie M Verified Purchase
April 23, 2018

Very good

Ryan K Verified Purchase
April 23, 2018

I went with Allivet on this product as it was rated well in lots of other places and the local pet stores have recently doubled the cost of the medicine so the better prices here certainly helped.

Ryan K Verified Purchase
April 23, 2018

I went with Allivet on this product as it was rated well in lots of other places and the local pet stores have recently doubled the cost of the medicine so the better prices here certainly helped.

Judith C Verified Purchase
March 23, 2018

Great for baby puppies until they are old enough to put on Bravecto.

Carole R Verified Purchase
February 9, 2018

works well where I live in the mountains of Maryland

Carole R Verified Purchase
February 9, 2018

works well where I live in the mountains of Maryland

Deanna A Verified Purchase
January 19, 2018

This is the best product I have found for keeping fleas under control on our dogs in the mostly warm and humid climate of Florida.

JACKIE P Verified Purchase
December 8, 2017

SITE WORKS VERY WELL

John C Verified Purchase
November 21, 2017

Best price for effect flea and tick control I have ever found.

Sandra S Verified Purchase
July 5, 2017

My first order for Advantage II

John L Verified Purchase
April 25, 2017

good price and works well

Jacquelynn B Verified Purchase
March 31, 2017

If you don't have ticks, this is all you need. Same formula, just very different doses, by weight, for dogs & cats. Be sure you know what you're doing. I've used it for over 25 years with good result. NEVER USE DOG TICK KILLER ON CATS OR CATS WILL DIE!

Maggie H Verified Purchase
February 16, 2017

Outstanding product. Does the job w no side effects on my dog.

MIKE s Verified Purchase
September 22, 2016

this was a return because I ordered the wrong thing. Fast easy no trouble courtesy what else is there

Elizabeth S Verified Purchase
September 11, 2016

very pleased with this newly found service and setting up on auto deliver is one less thing to worry about - very simple, very easy!

Jen g Verified Purchase
September 5, 2016

an excellent product for fighting fleas. more economical here than local

June H Verified Purchase
August 18, 2016

My dog is allergic to fleas. Not all medication works as well advantage ll.

Kathleen T Verified Purchase
August 10, 2016

works great on fleas.

Maggie H Verified Purchase
August 6, 2016

Wonderful product does the job of protecting my dog.

Theresa W Verified Purchase
July 20, 2016

I've used this on my other dogs with no problems. Has always worked.

Annmarie C Verified Purchase
June 29, 2016

Getting prescription renewed was easy. You faxed dr and they faxed back same day! Received order in 3 days!

Curtis Y Verified Purchase
June 25, 2016

took awhile

Jeanne M Verified Purchase
May 17, 2016

Best product

Carole B Verified Purchase
May 6, 2016

no problems with fleas or tick with this product. my dog is pretty much an inside dog but she could still attract those little buggers if not for advantage 11.

David B Verified Purchase
April 23, 2016

This works really well for us!

JACKIE P Verified Purchase
March 31, 2016

USED FOR YEARS W/NO FLEA PROBLEMS

Randi s Verified Purchase
December 15, 2015

It's affordable and better than similarly priced other topical products. I prefer an oral product but not all will eat it, so I use this for those animals. Lasts about 2 weeks only. Gets rid of about 80% of the fleas.

Theresa W Verified Purchase
October 19, 2015

Good value. I like purchasing from Allivet

Deborah C Verified Purchase
September 14, 2015

hate fleas. This is the only thing that keeps them away!

Jacki S Verified Purchase
September 11, 2015

Great price and service.

Patricia P Verified Purchase
July 31, 2015

My dog is allergic to flea and tick spot treatments. Vet recommended Advantage and a tick collar.

Kitty C Verified Purchase
May 18, 2015

Good flea preventive. We found that this works in our area better than other brands. Needs to be less expensive

Kerry J Verified Purchase
May 18, 2015

I used to use front line but fleas became immuned. Advantage is still working for me.

Tina B Verified Purchase
April 30, 2015

vet recommendation for dog with special medical needs.

Timkeeler Verified Purchase
March 24, 2015

I've been using Advantage for a few years now and it consistently keeps our house flea free.

Douglas H Verified Purchase
February 16, 2015

We use this and Revolution on a rotating basis. Works for us in Florida.

Steven G Verified Purchase
January 20, 2015

Southern Florida fleas are resistant to all the other topical treatments that I've tried, prescription and OTC. This seems to have done it -- now 48 hours since application and for the first time in MANY months, I do not detect fleas on any of my three dogs. And the price from this site was the best I found (plus quick shipment).

Sandra P Verified Purchase
January 17, 2015

More expensive at local pet store and Amazon charged tax on product.

Nancy S Verified Purchase
January 11, 2015

The best thing about Advantage 2 is that it kills ticks even though it doesn't advertise that it does. One of our dogs had a small tick on her neck last summer but it was DEAD and had not barely latched on. We feel it was the contact with the medicine that did the trick!!

Noriko M Verified Purchase
January 2, 2015

This was highly recommended by my vet as inexpensive and high efficiency flee prevention pills. My dogs are small and only Advantage has doses for dogs smaller than 10b

Kristi M Verified Purchase
November 19, 2014

Best stuff I have found for my dogs. Forget about frontline because this is way better.

Joanne S Verified Purchase
October 30, 2014

I only use advantix for my dogs it seems to be the only product that works correctly and the price at allivet is the best

Christine D Verified Purchase
October 18, 2014

Works, not a waste of money

Karen J Verified Purchase
October 17, 2014

While we don't have fleas and only rare cases of canine lice in Alaska, what I like about this is that it is easy to apply, has no obvious effect beyond protection, and meets the requirements for Doggy Day Camp.

Nathan P Verified Purchase
September 17, 2014

Same stuff as the one for cats, and if you measure it accurately using the weight of the cat it is much cheaper.

Ashley H Verified Purchase
September 11, 2014

Need to help my little kitty to be happy and healhly

John h Verified Purchase
August 30, 2014

I Have used for 2 years & will continue to use as we have had no problems with fleas & easy to apply. I'm really pleased with the results! I will use again!

Sierra n Verified Purchase
August 1, 2014

I called customer service(I believe I spoke to Jocelyn) and was extremely satisfied. I chose to purchase from you based on lowest price (including shipping). You also have products that I need. Advantage II for Dogs is the best.

Rebecca J Verified Purchase
August 19, 2013

Advantage II is great for the prevention and treatment of flea and lice, it works fast and very effectively

Questions & Answers