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Mexiletine Hydrochloride Capsule
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AutoShip Makes Pet Parenting Easier with automatic delivery and savings on every order!
Convenience: We contact your vet clinic when it’s time to renew your pet’s prescription.
Reminders: You’ll receive reminders prior to shipping, so you’ll have time to make changes.
Savings: Save on the initial order PLUS 5% on future deliveries.
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Item No.
49895
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Mexiletine Hydrochloride Capsule
By Teva
$0.80
Per Capsule
$0.40
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Product Overview
Mexiletine is an antiarrhythmic medication used in the treatment of ventricular arrhythmia. It is considered a class 1B sodium channel blocker.*Sold per capsule
Mexiletine is a class 1B, sodium channel blocker, anti-arrhythmia drug which is used to treat chronic ventricular arrhythmias in dogs. The mechanism of action is similar to lidocaine. Mexiletine is used to treat ventricular arrhythmias including PVC’s and ventricular tachycardia. If an animal has responded well to lidocaine during an acute episode, it is likely to respond well to mexiletine.
For use in dogs.
Features of Mexiletine:
- Prescribed for the treatment of ventricular arrhythmias, including ventricular tachycardia and PVCs
- Similar to lidocaine
- May be used in conjunction with sotalol or atenolol when monotherapy is inadequate
- May be used in the treatment of dilated cardiomyopathy in Doberman pinschers and in inherited cardiomyopathy in Boxers
- 85% reduction in premature ventricular contractions indicates a positive response to therapy
Mexiletine offers about an 85% bioavailability and is orally well-absorbed. It is partially metabolized by the liver (10%) and excreted through the feces, and the rest is excreted through the urine. Animals who have reduced cardiac output, severe disease of the kidneys, hepatic dysfunction, or have experienced acute myocardial infarction could experience a prolonged half-life.
The most frequently reported adverse reactions are GI tract-related and could include vomiting or nausea. These symptoms usually improve when Mexiletine is given with food.
Other potential reactions are central nervous system-related and could include:
Other potential reactions are central nervous system-related and could include:
- Cardiac symptoms (chest pain or PVCs)
- Shortness of breath
- Trembling
- Loss of balance
- Dizziness
Mexiletine Hydrochloride (mexiletine)
Overdose with mexiletine carries a significant risk of toxicity. It is reported in the human literature that central nervous system signs precede cardiovascular signs. In experimental work in dogs, a four fold overdose consistently produced CNS signs within 10 minutes of oral administration. If recognized in time, GI emptying protocol should be attempted in conjunction with urinary acidification and supportive care.
Mexiletine should be cautiously administered to animals with:
- Seizure disorders
- Hypotension
- Liver dysfunction
- Myocardial infarction
- Congestive heart failure
- Cardiogenic shock
- Abnormal sinus node function
- Abnormal intraventricular conduction
- 2nd or 3rd degree AV heart block
Sold by the capsule in strengths of 150mg, 200mg, and 250mg.
Teva
Follow your veterinarian's recommendations for administration.
Use as prescribed by your vet.
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About This Product
Customer Reviews
4.9
35 reviews
5
33
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Verified Purchase
Our 2 year old Boxer has a form of Heart Disease, this is one of the many meds that keep her at the pace she deserves:)
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Great stuff!
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My girl is a parvo/distemper survivor. She suffers from constant body spasms. There is no medication specifically for her condition. She has been taking Mexi since she was 3 mos and it is a life saver. Allivet has the best prices I have found.
Verified Purchase
Same great product as our vet has, but for a slightly lower price
Verified Purchase
This is a fairly hard to find medication. I was thrilled to find it at Allivet and for a great price😛!
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There was a delay with the meds but the problem was on the Vet side. Allivet kept trying every day to reach them, instead of giving up on the first try...great service!
Verified Purchase
This drug has worked wonderfully to lessen the severity of my dog’s ventricular arrhythmias. He’s been on it for a few months and has not been panting or having fast heartbeats while on it.
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My Boxer has a heart condition and requires this medication. This medication is not easy to find.
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very few pharmacies have this dosing, human pharmacies do not, and compounding is expensive!
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Cheaper price here then at vet
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RX for our Rottie!
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My older dog needs this medication to help control an arrhythmia. It is very expensive (even more so at human pharmacies) and difficult to find at most pet pharmacies. Allivet has the best price I have been able to find for this medication.
Verified Purchase
i BUY THIS PRODUCT FOR MY 9 YEAR OLD bORDER cOLLIE WHO HAS ARRYTHMIA AND HAS HAD HEART PROBLEM SINCE 2016. IT WORKS W/ QUARTERLY EKG'S. HIGHLY RECOMMEND!
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Saved My Fur Baby !!!!
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GREAT FAST DELIVERY!!
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Fast delivery and good prices
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good value
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Much cheaper to buy from Allivet, and timely arrival. No hassle to order. easy intuitive web site.
Verified Purchase
After our Vet diagnosed our dog with Cardiomyopathy and prescribed these capsules to our 10 year old bulldog she is having the time of her life... I guess she was feeling bad and we hadn't noticed but after she started her treatment with Mexiletine she is happy, playful and full of energy. I don't know how long she will be around but I am sure her quality of life is a whole lot better.
Verified Purchase
Delievery was delayed and they credited my account. Very pleased with service and will sign up for the auto ship.
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Recommended product for dog who is dignose with CHF & DCH
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Great price & easy refills. Comes in about a week.
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Great price! Needed this for my 9 yo boxer with cardiomyopathy and ventricular tachycardia. Fast shipping!
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It has saved me $100.00
Verified Purchase
great pricing
Verified Purchase
My Boxer, Duke, needed this medication after being recently diagnosed with a heart condition. This medication was hard to find at an onsite pharmacy. Allivet was able to provide it as well as his other needed medication. Thank you for making the process easy and for getting the medication to me promptly. I hope to spend quality years with Duke and obtaining this medication should help do just that!
Verified Purchase
Amazing price and fast shipping!
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Our 8 year old Dobe was recently diagnosed with Dilated Cardiomyopathy and this drug is to help treatment of ventricular arrhythmias.
Verified Purchase
The folks at Allivet are polite and helpful, their prices are much better than the local vet and they ship fast. You couldn't ask for more.
Verified Purchase
Prescribed by our Vet Cardiologist.
Verified Purchase
I was purchasing this from a local pharmacy but found the price to be much better at Allivet...I also just signed up for auto ship which is convenient and saves 5%...Happy Customer
Verified Purchase
Great price. Fast service. Consistent pharm. company.
Verified Purchase
Highly useful for ventricular premature contractions (VPC) in canines. Though it often has serious side effects so owners must be vigilant to observe and report any such findings to their board certified cardiologist. Our dog did not experience any side effects and it has worked very well on him.
Verified Purchase
My dog Shaka has a heart condition, and this is by far the best pricing I've found. The customer service support is great!
Verified Purchase
Allivet was out of stock when I placed my order. They immediately notified me and let me know when they would have it. It was extremely important that I received the medicine by a certain date, before my dog ran out of his currently filled rx. Allivet customer service and shipping time are both excellent! Very satisfied with their products. Very satisfied with Allivet!